And another addendum: As expected, if I switch off Qt stuff: -DVTK_USE_QT=OFF -DVTK_USE_QVTK=OFF -DVTK_USE_QTOPENGL=OFF the 'import vtk' works... I'm still trying to get behind this bug, next thing I'll try to build Qt, but not QVTK... Cheers, Thorben