# User:Ramirez

## Tuning Parameters

### Optimizers

"[...] In order to get some insight on how to tune the parameters for your optimization, probably the best thing to do is to study the characteristics of the Metric when computed over your images. Please find attached a small program that allows you to explore the values of the metric using a translation transform. You want to plot these values in order to get a feeling on the level of noise of the Metric, the presence of local minima, and the overall reproducibility of the Metric function itself. (you will have to convert the dimension to 3D, since the example was configured for 2D)

Please run this program first using the *same* input image as fixed and moving images, and let the translation be evaluated for a range that is close to 1/2 of the image extent (physical extent in millimeters).

Plot the values using your favorite plotting program. (anything from GNUPlot to Excel).

For examples on how these plot will look like, please take a look at the course in Image Registration:

```    http://www.cs.rpi.edu/courses/spring04/imagereg/
```

In particular, look at lectures 8 and 9.

[...] It is not productive to fight with the registration optimization until you find a way of generating relatively smooth Metric plots. Note that this is just an exercise on learning how to tune the parameters. Once you figure out the parameters, you will not need to plot the Metric anymore.

Make sure that origin and spacing are correctly set in your images before you start computing all these metric plots."

```#include "itkImage.h"
#include "itkImageFileWriter.h"
#include "itkMattesMutualInformationImageToImageMetric.h"
#include "itkTranslationTransform.h"
#include "itkLinearInterpolateImageFunction.h"

int main( int argc, char * argv[] )
{
if( argc < 3 )
{
std::cerr << "Usage: " << std::endl;
std::cerr << argv[0] << "  fixedImage  movingImage" << std::endl;
return 1;
}

const     unsigned int   Dimension = 2;
typedef   unsigned char  PixelType;

typedef itk::Image< PixelType, Dimension >   ImageType;
typedef itk::Image< PixelType, Dimension >   ImageType;