Hi Clinton, the path for the cache entry was incorrect as: QT_QTDESIGNER_INCLUDE_DIR:PATH=D:/Developer/Releases/MinGW/SHARED/Qt/QtDesigner should have been: QT_QTDESIGNER_INCLUDE_DIR:PATH=D:/Developer/Releases/MinGW/SHARED/Qt/include/QtDesigner vtkQtChart, QVTK and QVTKWidgetPlugin are now building thanks, Dean