[Insight-users] B-Splines registration with fixed points

[Albert Gubern Mérida]

Hi all,

I am currently working in Breast MRI registration between different
patients, especially interested in the alignment of body area (thorax +
pectoral muscles). The first step of my registration consist of a
translation to align the sternum, which gives a good initial alignment of
the pectoral muscles. In the following link you can see an example of one
slice with the sternum indicated with a white cross:
http://imageshack.us/photo/my-images/220/breastmristernum.png/. After the
translation step with the pectorals already "rigidly" aligned I apply
non-rigid b-splines registration to the whole volumes. It works well in some
cases, but in others, especially of course when the differences are high
between fixed and moving images, the non-rigid registration move the sternum
point and the pectorals are not aligned anymore.

I have thought that not allowing the non-registration the move of the
sternum point and the ones close to it could be a good solution for such
problem. However, I have taken a look to the classes and the mailing list
but I have not found any direct/easy example to how to do that.

Could anyone give me some advice? Does a easy way to do it exist or I should
modify the classes involved in the registration framework? Which ones should
I take a look?

Thanks in advance,

Albert
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