[Insight-users] Registration of one sub-brain to full-brain

[brian avants]

Hello Erik

You may want to try changing the number of resolutions employed in the
multi-resolution pyramid used to perform the registration.   In
addition, you may want to try switching the role of the fixed/moving
image.  We are currently revising the registration framework so now is
a good time to bring these types of issues up and work with us on
improving registration performance.

Brian


On Thu, Oct 21, 2010 at 4:35 AM, Erik Tuerke <tuerke at cbs.mpg.de> wrote:
> Hi!
>
> I want to register one hemisphere (actually 30 slices of 0.75 mm) to a
> fullbrain scan (30 slices of 0.75mm, but shifted to superior for about 5 mm)
> . Currently i am using a MattesMutualInformationImageToImage metric, a
> RegularStepGradientDescentOptimizer and a VersorRigid3DTransform.
>
> Prior to the registration the hemisphere is roughly aligned to the fullbrain
> (only needs translation of few mm and little rotation). If i start the
> registration the optimizer finishes with a rotation of about 90 deg x and y.
> I also tried a VersorRigid3DOptimizer and a NormalizedCorrelation with
> almost the same result.
>
> The scalefactors of my optimizer are:
>               optimizerScaleRegularStepGradient[0] = 1.0;
>               optimizerScaleRegularStepGradient[1] = 1.0;
>               optimizerScaleRegularStepGradient[2] = 1.0;
>               optimizerScaleRegularStepGradient[3] = 1.0/1000.0;
>               optimizerScaleRegularStepGradient[4] = 1.0/1000.0;
>               optimizerScaleRegularStepGradient[5] = 1.0/1000.0;
>
> I guess the itk examples are proposing the same values.
> Is there any trick to apply such a sub-brain registration to a full-brain
> registration. The worrying thing is that SPM gets it right :-(
>
> Thanks and best regards!!
>
> --
> Erik Tuerke
> Department of Neurophysics Max-Planck-Institute for Human Cognitive and
> Brain Sciences
> Stephanstrasse 1A
> 04103 Leipzig
> Germany Tel: +49 341 99 40-2440
> Email: tuerke at cbs.mpg.de
> www.cbs.mpg.de
>
>
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