[Insight-users] multiresolution levelset registration bug

[Lyubomir Zagorchev]

The LevelSetMotionRegistrationFunction generates an error
if a MultiResolutionPDEDeformableRegistration is used with
a LevelSetMotionRegistrationFilter. This is because the
m_MovingImageSmoothingFilter in

template <class TFixedImage, class TMovingImage,
class TDeformationField>
void LevelSetMotionRegistrationFunction<
TFixedImage,TMovingImage,TDeformationField>
::InitializeIteration()

does not get updated correctly in the transition from
coarse to fine resolution. As a result, the multiresolution
registration with the levelset filter works fine at the
coarsest resolution and crashes erratically at higher
resolutions.

Could you please verify this with the attached example?
I am running ITK 2.8.1 with Visual Studio 2005.

One possible fix is to recreate the smoothing filter every
time when InitializeIteration() is invoked (once per level)
but I am not sure if there isn't a better approach.

Could you please let me know what is the best fix?

Thank you,

Lyubomir


#include "itkImageFileReader.h"
#include "itkImageFileWriter.h"
#include "itkLevelSetMotionRegistrationFilter.h"
#include "itkMultiResolutionPDEDeformableRegistration.h"
#include "itkHistogramMatchingImageFilter.h"
#include "itkCastImageFilter.h"
#include "itkWarpImageFilter.h"
#include "itkLinearInterpolateImageFunction.h"
#include "itkExceptionObject.h"

const unsigned int Dimension = 3;

  class CommandIterationUpdate : public itk::Command
  {
  public:
    typedef  CommandIterationUpdate   Self;
    typedef  itk::Command             Superclass;
    typedef  itk::SmartPointer<CommandIterationUpdate>  Pointer;
    itkNewMacro( CommandIterationUpdate );
  protected:
    CommandIterationUpdate() {};

    typedef itk::Image< float, Dimension > InternalImageType;
    typedef itk::Vector< float, Dimension >    VectorPixelType;
    typedef itk::Image<  VectorPixelType, Dimension > DeformationFieldType;

		typedef itk::LevelSetMotionRegistrationFilter<
															InternalImageType,
															InternalImageType,
															DeformationFieldType> RegistrationFilterType;
  public:

    void Execute(itk::Object *caller, const itk::EventObject & event)
      {
        Execute( (const itk::Object *)caller, event);
      }

    void Execute(const itk::Object * object, const itk::EventObject & event)
      {
         const RegistrationFilterType * filter =
          dynamic_cast< const RegistrationFilterType * >( object );
        if( !(itk::IterationEvent().CheckEvent( &event )) )
          {
          return;
          }
        std::cout << filter->GetMetric() << std::endl;
      }
  };


int main( int argc, char *argv[] )
{
  if( argc < 4 )
    {
    std::cerr << "Missing Parameters " << std::endl;
    std::cerr << "Usage: " << argv[0];
    std::cerr << " fixedImageFile movingImageFile ";
    std::cerr << " outputImageFile " << std::endl;
    return 1;
    }

  typedef short PixelType;

  typedef itk::Image< PixelType, Dimension >  FixedImageType;
  typedef itk::Image< PixelType, Dimension >  MovingImageType;
  typedef itk::Image< float, Dimension > JacobianImageType;

  typedef itk::ImageFileReader< FixedImageType  > FixedImageReaderType;
  typedef itk::ImageFileReader< MovingImageType > MovingImageReaderType;

  FixedImageReaderType::Pointer fixedImageReader   =
    FixedImageReaderType::New();
  MovingImageReaderType::Pointer movingImageReader =
    MovingImageReaderType::New();

  fixedImageReader->SetFileName( argv[1] );
  movingImageReader->SetFileName( argv[2] );

  typedef float InternalPixelType;
  typedef itk::Image< InternalPixelType, Dimension > InternalImageType;
  typedef itk::CastImageFilter< FixedImageType,
                                InternalImageType > FixedImageCasterType;
  typedef itk::CastImageFilter< MovingImageType,
                                InternalImageType > MovingImageCasterType;

  FixedImageCasterType::Pointer fixedImageCaster   =
    FixedImageCasterType::New();
  MovingImageCasterType::Pointer movingImageCaster =
    MovingImageCasterType::New();

  fixedImageCaster->SetInput( fixedImageReader->GetOutput() );
  movingImageCaster->SetInput( movingImageReader->GetOutput() );

  typedef itk::HistogramMatchingImageFilter<
                                    InternalImageType,
                                    InternalImageType >   MatchingFilterType;
  MatchingFilterType::Pointer matcher = MatchingFilterType::New();

  matcher->SetInput( movingImageCaster->GetOutput() );
  matcher->SetReferenceImage( fixedImageCaster->GetOutput() );
  matcher->SetNumberOfHistogramLevels( 1024 );
  matcher->SetNumberOfMatchPoints( 7 );
  matcher->ThresholdAtMeanIntensityOn();

  typedef itk::Vector< float, Dimension >    VectorPixelType;
  typedef itk::Image<  VectorPixelType, Dimension > DeformationFieldType;

	typedef itk::LevelSetMotionRegistrationFilter<
														InternalImageType,
														InternalImageType,
														DeformationFieldType> RegistrationFilterType;

  RegistrationFilterType::Pointer filter = RegistrationFilterType::New();

  CommandIterationUpdate::Pointer observer = CommandIterationUpdate::New();
  filter->AddObserver( itk::IterationEvent(), observer );

  typedef itk::MultiResolutionPDEDeformableRegistration<
                                InternalImageType,
                                InternalImageType,
                                DeformationFieldType >
MultiResRegistrationFilterType;
  MultiResRegistrationFilterType::Pointer multires =
MultiResRegistrationFilterType::New();
  multires->SetRegistrationFilter( filter );
  multires->SetNumberOfLevels( 3 );
  multires->SetFixedImage( fixedImageCaster->GetOutput() );
  multires->SetMovingImage( matcher->GetOutput() );

  unsigned int nIterations[4] = { 10, 20, 50, 50 };
  multires->SetNumberOfIterations( nIterations );
  multires->Update();

  typedef itk::WarpImageFilter<
                          MovingImageType,
                          MovingImageType,
                          DeformationFieldType  >     WarperType;
  typedef itk::LinearInterpolateImageFunction<
                                   MovingImageType,
                                   double          >  InterpolatorType;
  WarperType::Pointer warper = WarperType::New();
  InterpolatorType::Pointer interpolator = InterpolatorType::New();
  FixedImageType::Pointer fixedImage = fixedImageReader->GetOutput();

  warper->SetInput( movingImageReader->GetOutput() );
  warper->SetInterpolator( interpolator );
  warper->SetOutputSpacing( fixedImage->GetSpacing() );
  warper->SetOutputOrigin( fixedImage->GetOrigin() );
  warper->SetDeformationField( multires->GetOutput() );

  // Write warped image out to file
  typedef unsigned short  OutputPixelType;
  typedef itk::Image< OutputPixelType, Dimension > OutputImageType;
  typedef itk::CastImageFilter<
                        MovingImageType,
                        OutputImageType > CastFilterType;
  typedef itk::ImageFileWriter< OutputImageType >  WriterType;

  WriterType::Pointer      writer =  WriterType::New();
  CastFilterType::Pointer  caster =  CastFilterType::New();

  writer->SetFileName( argv[3] );

  caster->SetInput( warper->GetOutput() );
  writer->SetInput( caster->GetOutput() );
  writer->Update();

  if( argc > 4 ) // if a fourth line argument has been provided...
    {

    typedef itk::ImageFileWriter< DeformationFieldType > FieldWriterType;

    FieldWriterType::Pointer fieldWriter = FieldWriterType::New();
    fieldWriter->SetFileName( argv[4] );
    fieldWriter->SetInput( multires->GetOutput() );

    try
      {
      fieldWriter->Update();
      }
    catch ( itk::ExceptionObject e )
      {
      e.Print( std::cerr );
      }
    }

  return 0;
}