[Insight-users] help with cardiac CT registration

[hariharan ganesh lalgudi]

hello,

   I am trying to register cardiac CT images (cubes in a cardiac cycle) 
based on "Deformableregistration7" example in itk(The one using 
B-splines). The physical size of the dataset is 220x220x130 mm.
With the No. of control point being 5x5x5  it takes about a day to 
register 2 cubes. The reduction in MSE (before and after registration) is also not 
much.

   To have a reasonable control point spacing (20x20x20 mm) No. of control 
points needs to be atleast 10x10x10. With the number of parameters being 
so high, I guess it would take much longer time to register two cubes. I 
was wondering if it would take so long for registration or if I am doing 
something wrong. Does have itk have hierarchical B-splines implemented?

I am also looking for some tips on registering cardiac cubes using tools 
in itk.

Any help would be appreciated.

Thanks,
Hari