TubeTK/TBI Data

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Image Format

Images are presented in the nii format. Each image can thus be loaded directly by any program that supports nii format, including most ITK and VTK-based applications such as Slicer.

There are two patients. For each of them there are data sets for the Acute and Chronic Stage: For each stage there are datas for 4 modalities:

  1. Fluid-attenuated inversion recovery (FLAIR) data set: Fluid-attenuated inversion recovery (FLAIR) is an advanced magnetic resonance imaging sequence that reveals tissue T2 prolongation with cerebrospinal fluid suppression, allowing detection of superficial brain lesions [1].
  1. Fluid-attenuated inversion recovery (FLAIR) data set: Fluid-attenuated inversion recovery (FLAIR) is an advanced magnetic resonance imaging sequence that reveals tissue T2 prolongation with cerebrospinal fluid suppression, allowing detection of superficial brain lesions [2].


We don`t have "susceptibility-weighted imaging (SWI)" and DTI data at the moment.


Data Set for Patient A
Flair GRE T1 T2
Acute Time Point Cell 2 Cell 3
Chronic Time Point Cell B Cell C


Terms of Use

This database is provided without charge for use in research, teaching, and commercial developments that advance the medical field. Uses outside of the medical field require prior written approval from Dr. Elizabeth Bullitt. These data may not be redistributed except when a few cases are distributed as part of an electronic publication in which the author of the publication has added significant value to the publication, beyond the value of the cases being redistributed. In all other situations, citations and links to this webpage should be used.

We request that any publication or project that uses this data do the following:

a) Cite the following paper

     Bullitt E, Zeng D, Gerig G, Aylward S, Joshi S, Smith JK, Lin W, Ewend MG (2005) Vessel tortuosity and brain tumor malignancy: A blinded study. Academic Radiology 12:1232-1240 

as an example of how this kind of healthy image database can be used,

b) Include the following text (or something similar) in your acknowledgements

     "The MR brain images from healthy volunteers used in this paper were collected and made available by the CASILab at The University of North Carolina at Chapel Hill and were distributed by the MIDAS Data Server at Kitware, Inc."

Data Illustrations

Sample images from a typical healthy patient are shown below.