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<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Hi,<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p>&nbsp;</o:p></span></font></p>

<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>I have faced (or am facing actually) the
same problem. I found it espacially confusing that the itk::Image has a
GetDirection and GetOrigin method, however these are apparently not used in the
TransformContinuousIndexToPhysicalPoint method. If you want that, you should
use the itk::OrientedImage. But be warned, in the calculation of the metric the
orientation is ignored while computing the gradient. I concluded that it is
best to resample your image such that both images, fixed and moving, have the
same orientation. It is a bit cumbersome, but it works and the results should not
be too different from the results you would get if the registration would
properly using the image orientation. Still I would like that orientation and
origin are consistently used within ITK (at the very least this behavior
should&nbsp; be properly documented!).<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p>&nbsp;</o:p></span></font></p>

<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>best,<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Jeroen<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p>&nbsp;</o:p></span></font></p>

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face="Times New Roman"><span style='font-size:12.0pt'>

<hr size=2 width="100%" align=center tabindex=-1>

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<p class=MsoNormal><b><font size=2 face=Tahoma><span style='font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font size=2
face=Tahoma><span style='font-size:10.0pt;font-family:Tahoma'>
insight-users-bounces+j.s.wijnhout=lumc.nl@itk.org
[mailto:insight-users-bounces+j.s.wijnhout=lumc.nl@itk.org] <b><span
style='font-weight:bold'>On Behalf Of </span></b>Thees, Sebastian<br>
<b><span style='font-weight:bold'>Sent:</span></b> Friday, February 01, 2008
9:50 AM<br>
<b><span style='font-weight:bold'>To:</span></b> insight-users@itk.org<br>
<b><span style='font-weight:bold'>Subject:</span></b> [Insight-users] image
orientation and registration, current status ?</span></font><o:p></o:p></p>

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<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><o:p>&nbsp;</o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=DE style='font-size:10.0pt;
font-family:Arial'>Dear itk developer,<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=DE style='font-size:10.0pt;
font-family:Arial'><o:p>&nbsp;</o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>I am a new user of itk - so first at all, thanks for
this fantastic library and for providing it open source ! I was really
surprised to found such a comprehensive tool for image registration (and
segmentation of course) on the web.<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'><o:p>&nbsp;</o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>However, from the medical-image-analysis point of
view, there is one thing I could absolutely not understood. Why do you ignore
image orientation in image registration ?!?!? It so extremely limits the easy
use of the toolkit. Even an option to use the orientation cosines should be
present.<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'><o:p>&nbsp;</o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>My question: Is there an example implementation of
&nbsp;the solution outlined in http://public.kitware.com/Bug/view.php?id=5081
by Luis Ibanez, so that I can continue with that for other metrics ? Or does a
patch exsists ? Hints, code snippets (i am not too much familiar with itk and
template techniques), etc are welcome ...<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'><o:p>&nbsp;</o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>best regards,<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>Sebastian<o:p></o:p></span></font></p>

<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'><o:p>&nbsp;</o:p></span></font></p>

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