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<TITLE>itkDeformableSimplex3DFilter: different spacing of image data </TITLE>
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<P><FONT SIZE=2 FACE="Arial">Hello,</FONT>
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<P><FONT SIZE=2 FACE="Arial">I'm using the itkDeformableSimplex3DFilter.</FONT>
<BR><FONT SIZE=2 FACE="Arial">It is clear from the documentation that this filter currently assumes that the spacing of the input image is 1. The image data I use, do not have equal resolution in X, Y, and Z direction. In order to be able to use the DeformableSimplexMesh algorithm I'm currently resampling the image data such that the spacing is 1 in all directions. However, resampling of the data results (in my case) in large datasets, containing redundant information. The resampling therefore causes memory problems and is not a very elegant solution. </FONT></P>
<P><FONT SIZE=2 FACE="Arial">It would favorable to compensate for the different resolutions in the itkDeformableSimplex3DFilter-algorithm itself and therefore eliminating the need for resampling of the image data.</FONT></P>
<P><FONT SIZE=2 FACE="Arial">Has anyone encountered similar problems and solved this problem by taking into account different spacings of the image data when deforming a mesh? Or is there another itk-class that does take into account different spacings when deforming objects?</FONT></P>
<P><FONT SIZE=2 FACE="Arial">I know that all the gradientFilters (for example</FONT> <FONT COLOR="#000000" SIZE=2 FACE="Arial">GradientMagnitudeImageFilter, GradientMagnitudeRecursiveGaussianImageFilter) do take into account different spacings, so computation of gradient information in image data with different X,Y,Z spacing is not problem.</FONT></P>
<P><FONT COLOR="#000000" SIZE=2 FACE="Arial">Thanks in advance for your help!</FONT>
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<P><FONT COLOR="#000000" SIZE=2 FACE="Arial">Kind regards, </FONT>
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<P><FONT COLOR="#000000" SIZE=2 FACE="Arial Unicode MS">Maartje M. Nillesen</FONT>
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<P><FONT COLOR="#000000" SIZE=2 FACE="Arial Unicode MS">Radboud University Nijmegen Medical Centre</FONT>
<BR><FONT COLOR="#000000" SIZE=2 FACE="Arial Unicode MS">833 Clinical Physics Laboratory, Dep. of Pediatrics</FONT>
<BR><FONT COLOR="#000000" SIZE=2 FACE="Arial Unicode MS">Nijmegen, The Netherlands</FONT>
<BR><FONT COLOR="#000000" SIZE=2 FACE="Arial Unicode MS">T +31 24 3668967</FONT>
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