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<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>Hello,<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>I’m trying to create a program where I want to
use the Viola-Wells (Mutual Information algorithm) and the affine registration.<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>In the examples of ITK I found the MI algorithm and
the affine algorithm but both are using different Optimizer. I tried to match all
the things together in one cpp-file so that it should work but it doesn’t<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>I got this error message on the command line:<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'> “MutualInformationImageToImageMetric(018CBC40):
All the sampled point mapped to outside of the moving image”<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>Could someone help me? I think it is something simple,
but I haven’t got a clue.<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>Cheers,<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>markus<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'>This is the source code<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span lang=EN-GB style='font-size:
10.0pt;font-family:Arial'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 color=green
face="Courier New"><span lang=EN-GB style='font-size:10.0pt;font-family:"Courier New";
color:green'> //start Viola-Wells mutual information<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> metric->SetFixedImageStandardDeviation(
0.4 );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
metric->SetMovingImageStandardDeviation( 0.4 );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=green><span style='color:green'>//load pictures<o:p></o:p></span></font></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>typedef</span></font>
itk::ImageFileReader< FixedImageType > FixedImageReaderType;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>typedef</span></font>
itk::ImageFileReader< MovingImageType > MovingImageReaderType;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> FixedImageReaderType::Pointer
fixedImageReader = FixedImageReaderType::New();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> MovingImageReaderType::Pointer
movingImageReader = MovingImageReaderType::New();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> fixedImageReader->SetFileName(
arg1 );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
movingImageReader->SetFileName( arg2 );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=green><span style='color:green'><o:p></o:p></span></font></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>typedef</span></font>
itk::NormalizeImageFilter< <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
FixedImageType, <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
InternalImageType <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
> FixedNormalizeFilterType;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>typedef</span></font>
itk::NormalizeImageFilter< <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
FixedImageType, <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
InternalImageType <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
> MovingNormalizeFilterType;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
FixedNormalizeFilterType::Pointer fixedNormalizer =
FixedNormalizeFilterType::New();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
MovingNormalizeFilterType::Pointer movingNormalizer =
MovingNormalizeFilterType::New();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>typedef</span></font>
itk::DiscreteGaussianImageFilter<<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
InternalImageType, <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
InternalImageType<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
> GaussianFilterType;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
GaussianFilterType::Pointer fixedSmoother = GaussianFilterType::New();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> GaussianFilterType::Pointer
movingSmoother = GaussianFilterType::New();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> fixedSmoother->SetVariance(
2.0 );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
movingSmoother->SetVariance( 2.0 );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
fixedNormalizer->SetInput( fixedImageReader->GetOutput() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> movingNormalizer->SetInput(
movingImageReader->GetOutput() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
fixedSmoother->SetInput( fixedNormalizer->GetOutput() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> movingSmoother->SetInput(
movingNormalizer->GetOutput() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
registration->SetFixedImage( fixedSmoother->GetOutput() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> registration->SetMovingImage(
movingSmoother->GetOutput() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
fixedNormalizer->Update();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> FixedImageType::RegionType
fixedImageRegion = fixedNormalizer->GetOutput()->GetBufferedRegion();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
registration->SetFixedImageRegion( fixedImageRegion );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=green><span style='color:green'>//end of Viola Wells MI<o:p></o:p></span></font></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 color=green
face="Courier New"><span lang=EN-GB style='font-size:10.0pt;font-family:"Courier New";
color:green'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=green><span style='color:green'>//start with affine part<o:p></o:p></span></font></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>typedef</span></font>
itk::CenteredTransformInitializer< TransformType,
FixedImageType,MovingImageType > TransformInitializerType;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> TransformInitializerType::Pointer
initializer = TransformInitializerType::New();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> initializer->SetTransform(
transform );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
initializer->SetFixedImage( fixedImageReader->GetOutput() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
initializer->SetMovingImage( movingImageReader->GetOutput() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> initializer->MomentsOn();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
initializer->InitializeTransform();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
registration->SetInitialTransformParameters(transform->GetParameters() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>double</span></font> translationScale = 1.0
/ 1000.0;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>unsigned</span></font> <font color=blue><span
style='color:blue'>int</span></font> maxNumberOfIterations = atoi( arg7 );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=blue><span style='color:blue'>typedef</span></font>
OptimizerType::ScalesType OptimizerScalesType;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
OptimizerScalesType optimizerScales( transform->GetNumberOfParameters() );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=green><span style='color:green'>//rotation matrix factor<o:p></o:p></span></font></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
optimizerScales[0] = 1.0;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
optimizerScales[1] = 1.0;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=green><span style='color:green'>//rotation center<o:p></o:p></span></font></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
optimizerScales[2] = 1.0;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
optimizerScales[3] = 1.0;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <font
color=green><span style='color:green'>//components of the translation<o:p></o:p></span></font></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> optimizerScales[4]
= translationScale;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
optimizerScales[5] = translationScale;<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
optimizer->SetScales( optimizerScales );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> <o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> optimizer->SetLearningRate(
15.0 );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
optimizer->SetNumberOfIterations( maxNumberOfIterations );<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> optimizer->MaximizeOn();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'><o:p> </o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'>
CommandIterationUpdate::Pointer observer = CommandIterationUpdate::New();<o:p></o:p></span></font></p>
<p class=MsoNormal style='text-autospace:none'><font size=2 face="Courier New"><span
lang=EN-GB style='font-size:10.0pt;font-family:"Courier New"'> optimizer->AddObserver(
itk::IterationEvent(), observer );<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face="Courier New"><span lang=EN-GB
style='font-size:10.0pt;font-family:"Courier New"'> </span></font><font
size=2 color=green face="Courier New"><span style='font-size:10.0pt;font-family:
"Courier New";color:green'>//end with affine part</span></font><font size=2
face=Arial><span lang=EN-GB style='font-size:10.0pt;font-family:Arial'><o:p></o:p></span></font></p>
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