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face=宋体>insight-users-request@itk.org,您好!</FONT> </FONT>
<DIV> </DIV>
<DIV> I found that the derived class of HistogramImageToImageMetric,
such as: MutualInformationHistogramImageToImageMetric</DIV>
<DIV>and NormalizedMutualInformationHistogramImageToImageMetric, has no method
of GetDerivate(). Does this mean that we</DIV>
<DIV>could not apply RegularStepsGradientDescentOptimizer as an optimzer to
registration work when using such metric. Is there </DIV>
<DIV>any prinprle for one metric to choose a propriate optimizer.</DIV>
<DIV> </DIV>
<DIV> Thinks a lot :)</DIV></BODY></HTML>