<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:st1="urn:schemas-microsoft-com:office:smarttags" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv=Content-Type content="text/html; charset=us-ascii">
<meta name=Generator content="Microsoft Word 11 (filtered medium)">
<!--[if !mso]>
<style>
v\:* {behavior:url(#default#VML);}
o\:* {behavior:url(#default#VML);}
w\:* {behavior:url(#default#VML);}
.shape {behavior:url(#default#VML);}
</style>
<![endif]-->
<title>Message</title>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="PostalCode"
downloadurl="http://www.5iamas-microsoft-com:office:smarttags"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="State" downloadurl="http://www.5iamas-microsoft-com:office:smarttags"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="City" downloadurl="http://www.5iamas-microsoft-com:office:smarttags"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="Street" downloadurl="http://www.5iantlavalampft-com:office:smarttags"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="address" downloadurl="http://www.5iamas-microsoft-com:office:smarttags"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="PlaceType" downloadurl="http://www.5iantlavalamp.com/"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="PlaceName" downloadurl="http://www.5iantlavalamp.com/"/>
<o:SmartTagType namespaceuri="urn:schemas-microsoft-com:office:smarttags"
name="place" downloadurl="http://www.5iantlavalamp.com/"/>
<!--[if !mso]>
<style>
st1\:*{behavior:url(#default#ieooui) }
</style>
<![endif]-->
<style>
<!--
/* Font Definitions */
@font-face
{font-family:Batang;
panose-1:2 3 6 0 0 1 1 1 1 1;}
@font-face
{font-family:Tahoma;
panose-1:2 11 6 4 3 5 4 4 2 4;}
@font-face
{font-family:"\@Batang";
panose-1:0 0 0 0 0 0 0 0 0 0;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
margin-bottom:.0001pt;
font-size:12.0pt;
font-family:"Times New Roman";}
a:link, span.MsoHyperlink
{color:blue;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{color:purple;
text-decoration:underline;}
p
{mso-margin-top-alt:auto;
margin-right:0in;
mso-margin-bottom-alt:auto;
margin-left:0in;
font-size:12.0pt;
font-family:"Times New Roman";}
span.EmailStyle18
{mso-style-type:personal;
font-family:Arial;
color:windowtext;}
span.EmailStyle19
{mso-style-type:personal;
font-family:Arial;
color:navy;}
span.EmailStyle20
{mso-style-type:personal;
font-family:Arial;
color:navy;}
span.EmailStyle22
{mso-style-type:personal-reply;
font-family:Arial;
color:navy;}
@page Section1
{size:8.5in 11.0in;
margin:1.0in 1.25in 1.0in 1.25in;}
div.Section1
{page:Section1;}
-->
</style>
<!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang=EN-US link=blue vlink=purple>
<div class=Section1>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>David and others:<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Here are some comments from Jay West at
Accuray on the Wiki page. Jay is on my program committee at SPIE so I will see
him this week and thank him for the comments.<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>David, can you update the page at your
convenience to reflect these comments? I am sure if you have some brief
questions you can ask Jay West directly, but I doubt he has time for long
discussions. But to me this is the beauty of open source as everything is open
for discussion, comment, and improvement.<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Kevin<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<div>
<div class=MsoNormal align=center style='text-align:center'><font size=3
face="Times New Roman"><span style='font-size:12.0pt'>
<hr size=2 width="100%" align=center tabindex=-1>
</span></font></div>
<p class=MsoNormal><b><font size=2 face=Tahoma><span style='font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font size=2
face=Tahoma><span style='font-size:10.0pt;font-family:Tahoma'> Jay West
[mailto:jwest@accuray.com] <br>
<b><span style='font-weight:bold'>Sent:</span></b> Thursday, February 09, 2006
2:32 PM<br>
<b><span style='font-weight:bold'>To:</span></b> Kevin Cleary<br>
<b><span style='font-weight:bold'>Subject:</span></b> Re: error prediction in
rigid body point based registration</span></font><o:p></o:p></p>
</div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><o:p> </o:p></span></font></p>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Hi Kevin,</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><br>
</span></font><font size=2 color=blue face=Arial><span style='font-size:10.0pt;
font-family:Arial;color:blue'>Sorry for the delay - as always, it's a struggle
to find free time here at Accuray. Here are my comments on the Wiki page:</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Definitions: 1: "homologus"
should read; homologous</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Definitions: 3: "homologus"
should read; homologous</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Definitions: 4 should read something like
"Expected target registration error: statistical expected value of TRE,
derived from distributions based on theoretical derivations or past
observation."</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Motivation: "root means square"
should read; "root mean square". Possibly reference Sibson '79 paper
for claim that FRE is independent of fiducial configuration.</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Motivation: "derived approximate
expression" should read "derived an approximate expression"</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Motivation: last line - "function of
target registration error" should read; "function of FLE". </span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Motivation: last line - "the the
fiducial points" should read; "the fiducial points"</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>David's suggestion: I agree that it's
important to handle the composition of transforms. There is no method of doing
this specified in the suggestion - I suggest referencing the TMI paper on this
by Calvin and me, published in 2004: "Designing optically tracked
instruments for image-guided surgery", Jay B. West and Calvin R. Maurer,
Jr., vol 23 (5), 533-545, May 2004.</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>What information is needed to compute TRE:
Assuming you're working in three dimensions, seems to be intuitive that
whatever formulation you use, you need </span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><br>
</span></font><font size=2 color=blue face=Arial><span style='font-size:10.0pt;
font-family:Arial;color:blue'>(a) The point at which you're calculating, in
some arbitrary coordinate system (three parameters)</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>(b) The principal axes of the fiducial
configuration: the page claims this can be done with 3 parameters - I would use
6 (two vectors, the third being the cross product of the first two) for
simplicity.</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>(c) The centroid of the fiducial
configuration (three parameters)</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>(d) The value of the moments of the
fiducial configuration about each axis (three parameters)</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Hence you need 12 parameters, including
the three which are arguments to the computation function. </span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>The answer to (1) is that yes, all rigid
body registration errors can be described with the same basic formulations,
assuming obviously that you're subject to the restrictions and happy with the
assumptions made in Fitzpatrick et al. </span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>For (2), yes, see the IEEE TMI paper I
mentioned above.</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Simplification: I agree with the
mathematical logic here. However, in many cases, especially those with moments
about the axes that vary greatly, this will result in a gross overestimation of
TRE at many places. I'm not really familiar with IGSTK, but I don't intuitively
see why maintaining ten floating point numbers and hence giving accurate TRE
estimated everywhere should be an enormous overhead. </span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>James' Suggestion: I agree that the name
should be something like "PredictTargetRegistrationError", or
"ExpectedTargetRegistrationError". </span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Stephen's Suggestion: Yes, the TRE work
assumes a rigid registration transform. It also assumes that the registration
method used is minimization of rms FRE between corresponding fiducial points.
If either of these assumptions is violated, the TRE formula no longer holds.
For deformable registration methods, it's not enough to simply approximate TRE
by looking at the registration transform as a locally rigid transform and
derive TRE point-by-point in this way. The trouble is that the transform is
derived in a different way, and so the TRE approximation is not valid. </span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Jay</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<blockquote style='margin-top:5.0pt;margin-right:0in;margin-bottom:5.0pt'>
<p class=MsoNormal style='margin-bottom:12.0pt'><font size=2 face=Tahoma><span
style='font-size:10.0pt;font-family:Tahoma'>-----Original Message-----<br>
<b><span style='font-weight:bold'>From:</span></b> Kevin Cleary <br>
<b><span style='font-weight:bold'>Sent:</span></b> Friday, January 06, 2006
6:48 PM<br>
<b><span style='font-weight:bold'>To:</span></b> Jay West<br>
<b><span style='font-weight:bold'>Subject:</span></b> RE: error prediction in
rigid body point based registration</span></font><o:p></o:p></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Jay – <o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>No particular deadline, but certainly by
the SPIE conference would be useful as several of the developers will be there<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>I do not know this person, but I do know
the person who heads the biophysics group and would be happy to check with him
if you like<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Kevin<o:p></o:p></span></font></p>
<div>
<div class=MsoNormal align=center style='text-align:center'><font size=3
face="Times New Roman"><span style='font-size:12.0pt'>
<hr size=2 width="100%" align=center tabIndex=-1>
</span></font></div>
<p class=MsoNormal><b><font size=2 face=Tahoma><span style='font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font size=2
face=Tahoma><span style='font-size:10.0pt;font-family:Tahoma'> Jay West
[mailto:jwest@accuray.com] <br>
<b><span style='font-weight:bold'>Sent:</span></b> Thursday, January 05, 2006
11:46 AM<br>
<b><span style='font-weight:bold'>To:</span></b> Kevin Cleary<br>
<b><span style='font-weight:bold'>Subject:</span></b> Re: error prediction in
rigid body point based registration</span></font><o:p></o:p></p>
</div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><o:p> </o:p></span></font></p>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Kevin,</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Sorry for the delay - it's still on my
list of things to do. Is there a deadline for this that I need to work to?</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>BTW, I'm about to interview a guy called
Zegang Dong for a medical physicist position here. His PhD is</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>from Georgetown Biophysics dept. - do you
know him, and if so, would you recommend him?</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Thanks</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'><br>
Jay</span></font><o:p></o:p></p>
</div>
<blockquote style='margin-top:5.0pt;margin-right:0in;margin-bottom:5.0pt'>
<p class=MsoNormal style='margin-bottom:12.0pt'><font size=2 face=Tahoma><span
style='font-size:10.0pt;font-family:Tahoma'>-----Original Message-----<br>
<b><span style='font-weight:bold'>From:</span></b> Kevin Cleary <br>
<b><span style='font-weight:bold'>Sent:</span></b> Thursday, January 05, 2006
8:41 AM<br>
<b><span style='font-weight:bold'>To:</span></b> Jay West<br>
<b><span style='font-weight:bold'>Subject:</span></b> RE: error prediction in
rigid body point based registration</span></font><o:p></o:p></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Jay<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Happy New Year! Any chance you can take a
look at this Wiki page and give us some feedback?<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>We have been getting things organized for
SPIE and I think it will be a good meeting<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:navy'>Kevin<o:p></o:p></span></font></p>
<div>
<p class=MsoNormal><font size=2 color=navy face="Courier New"><span
style='font-size:10.0pt;font-family:"Courier New";color:navy'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 color=navy face="Courier New"><span
style='font-size:10.0pt;font-family:"Courier New";color:navy'>------------------------------------------------------------------<br>
Kevin Cleary,
Ph.D.
Work phone: 202-687-8253<br>
Associate
Professor
Work fax: 202-784-3479<br>
Deputy Director <br>
<br>
Imaging Science and Information Systems (<st1:place w:st="on">ISIS</st1:place>)
Center<br>
Department of Radiology
Pager: 202-901-2033<br>
<st1:place w:st="on"><st1:PlaceName w:st="on">Georgetown</st1:PlaceName> <st1:PlaceType
w:st="on">University</st1:PlaceType> <st1:PlaceName w:st="on">Medical</st1:PlaceName>
<st1:PlaceType w:st="on">Center</st1:PlaceType></st1:place>
Cell phone: 202-294-3409<br>
<st1:Street w:st="on"><st1:address w:st="on">2115 Wisconsin Avenue, Suite 603</st1:address></st1:Street>
Home phone: 301-299-0788<br>
<st1:place w:st="on"><st1:City w:st="on">Washington</st1:City>, <st1:State
w:st="on">DC</st1:State>, <st1:PostalCode w:st="on">20007</st1:PostalCode></st1:place>
Home fax: 301-299-0789</span></font><font color=navy><span style='color:navy'><o:p></o:p></span></font></p>
<div>
<p class=MsoNormal><font size=3 color=navy face="Times New Roman"><span
style='font-size:12.0pt;color:navy'> <o:p></o:p></span></font></p>
</div>
<p class=MsoNormal><st1:place w:st="on"><font size=2 color=navy
face="Courier New"><span style='font-size:10.0pt;font-family:"Courier New";
color:navy'>ISIS</span></font></st1:place><font size=2 color=navy
face="Courier New"><span style='font-size:10.0pt;font-family:"Courier New";
color:navy'> center: </span></font><font color=navy><span style='color:navy'><a
href="http://www.isis.georgetown.edu/" title="http://www.isis.georgetown.edu/"><font
size=2 face="Courier New" title="http://www.isis.georgetown.edu/"><span
style='font-size:10.0pt;font-family:"Courier New"'>www.isis.georgetown.edu</span></font></a><br>
</span></font><font size=2 color=navy face="Courier New"><span
style='font-size:10.0pt;font-family:"Courier New";color:navy'>Research group: </span></font><font
color=navy><span style='color:navy'><a href="http://www.caimr.georgetown.edu/"
title="http://www.caimr.georgetown.edu/"><font size=2 face="Courier New"
title="http://www.caimr.georgetown.edu/"><span style='font-size:10.0pt;
font-family:"Courier New"'>www.caimr.georgetown.edu</span></font></a><br>
</span></font><font size=2 color=navy face="Courier New"><span
style='font-size:10.0pt;font-family:"Courier New";color:navy'>WashCAS: </span></font><font
color=navy><span style='color:navy'><a href="http://www.washcas.org/"
title="http://www.washcas.org/"><font size=2 face="Courier New"
title="http://www.washcas.org/"><span style='font-size:10.0pt;font-family:"Courier New"'>www.washcas.org</span></font></a><br>
</span></font><font size=2 color=navy face="Courier New"><span
style='font-size:10.0pt;font-family:"Courier New";color:navy'>Email: </span></font><font
color=navy><span style='color:navy'><a href="mailto:cleary@georgetown.edu"
title="mailto:cleary@georgetown.edu"><font size=2 face="Courier New"
title="mailto:cleary@georgetown.edu"><span style='font-size:10.0pt;font-family:
"Courier New"'>cleary@georgetown.edu</span></font></a><br>
</span></font><font size=2 color=navy face="Courier New"><span
style='font-size:10.0pt;font-family:"Courier New";color:navy'>-------------------------------------------------------------------</span></font><o:p></o:p></p>
</div>
<div>
<div class=MsoNormal align=center style='text-align:center'><font size=3
face="Times New Roman"><span style='font-size:12.0pt'>
<hr size=2 width="100%" align=center tabIndex=-1>
</span></font></div>
<p class=MsoNormal><b><font size=2 face=Tahoma><span style='font-size:10.0pt;
font-family:Tahoma;font-weight:bold'>From:</span></font></b><font size=2
face=Tahoma><span style='font-size:10.0pt;font-family:Tahoma'> Jay West
[mailto:jwest@accuray.com] <br>
<b><span style='font-weight:bold'>Sent:</span></b> Sunday, December 11, 2005
7:49 PM<br>
<b><span style='font-weight:bold'>To:</span></b> Kevin Cleary<br>
<b><span style='font-weight:bold'>Subject:</span></b> Re: error prediction in
rigid body point based registration</span></font><o:p></o:p></p>
</div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><o:p> </o:p></span></font></p>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Hi Kevin:</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Yes, I'd be happy to take a look at the
page and let you know my take on it. </span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Look forward to seeing you at SPIE in Feb.</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'>Regards</span></font><o:p></o:p></p>
</div>
<div>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'><br>
Jay</span></font><o:p></o:p></p>
</div>
<blockquote style='margin-top:5.0pt;margin-right:0in;margin-bottom:5.0pt'>
<p class=MsoNormal style='margin-bottom:12.0pt'><font size=2 face=Tahoma><span
style='font-size:10.0pt;font-family:Tahoma'>-----Original Message-----<br>
<b><span style='font-weight:bold'>From:</span></b> Kevin Cleary <br>
<b><span style='font-weight:bold'>Sent:</span></b> Thursday, December 08, 2005
11:26 AM<br>
<b><span style='font-weight:bold'>To:</span></b> Jay West<br>
<b><span style='font-weight:bold'>Subject:</span></b> error prediction in rigid
body point based registration</span></font><o:p></o:p></p>
<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'>Jay:<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'>Hope all is well at Accuray. I want to ask a favor of you. I
am the principal investigator of an NIH funded open source software project to
develop a software toolkit for image-guided surgery. As one of the parts of
this project, we are implementing a point based registration class. Would you
be so kind to take a look at the Wiki page on this and give me some feedback?
This is no hurry and I would be glad to give you some more background on the
project any time. We are planning a small demo at SPIE.<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 face=Arial><span style='font-size:10.0pt;
font-family:Arial'><a
href="http://public.kitware.com/IGSTKWIKI/index.php/Error_Prediction_in_Rigid-Body_Point-Based_Registration">http://public.kitware.com/IGSTKWIKI/index.php/Error_Prediction_in_Rigid-Body_Point-Based_Registration</a>
<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=2 color=blue face=Arial><span style='font-size:
10.0pt;font-family:Arial;color:blue'> </span></font> <o:p></o:p></p>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'>Thanks<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'>Kevin<o:p></o:p></span></font></p>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><o:p> </o:p></span></font></p>
<p class=MsoNormal><font size=2 face="Courier New"><span style='font-size:10.0pt;
font-family:"Courier New"'>------------------------------------------------------------------<br>
Kevin Cleary,
Ph.D.
Work phone: 202-687-8253<br>
Associate
Professor
Work fax: 202-784-3479<br>
Deputy Director <br>
<br>
Imaging Science and Information Systems (<st1:place w:st="on">ISIS</st1:place>)
Center<br>
Department of
Radiology
Pager: 202-901-2033<br>
<st1:place w:st="on"><st1:PlaceName w:st="on">Georgetown</st1:PlaceName> <st1:PlaceType
w:st="on">University</st1:PlaceType> <st1:PlaceName w:st="on">Medical</st1:PlaceName>
<st1:PlaceType w:st="on">Center</st1:PlaceType></st1:place>
Cell phone: 202-294-3409<br>
<st1:Street w:st="on"><st1:address w:st="on">2115 Wisconsin Avenue, Suite 603</st1:address></st1:Street>
Home phone: 301-299-0788<br>
<st1:place w:st="on"><st1:City w:st="on">Washington</st1:City>, <st1:State
w:st="on">DC</st1:State>, <st1:PostalCode w:st="on">20007</st1:PostalCode></st1:place>
Home fax: 301-299-0789</span></font><o:p></o:p></p>
<div>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'> <o:p></o:p></span></font></p>
</div>
<p class=MsoNormal><st1:place w:st="on"><font size=2 face="Courier New"><span
style='font-size:10.0pt;font-family:"Courier New"'>ISIS</span></font></st1:place><font
size=2 face="Courier New"><span style='font-size:10.0pt;font-family:"Courier New"'>
center: </span></font><a href="http://www.isis.georgetown.edu/"
title="http://www.isis.georgetown.edu/"><font size=2 face="Courier New"
title="http://www.isis.georgetown.edu/"><span style='font-size:10.0pt;
font-family:"Courier New"'>www.isis.georgetown.edu</span></font></a><br>
<font size=2 face="Courier New"><span style='font-size:10.0pt;font-family:"Courier New"'>Research
group: </span></font><a href="http://www.caimr.georgetown.edu/"
title="http://www.caimr.georgetown.edu/"><font size=2 face="Courier New"
title="http://www.caimr.georgetown.edu/"><span style='font-size:10.0pt;
font-family:"Courier New"'>www.caimr.georgetown.edu</span></font></a><br>
<font size=2 face="Courier New"><span style='font-size:10.0pt;font-family:"Courier New"'>WashCAS:
</span></font><a href="http://www.washcas.org/" title="http://www.washcas.org/"><font
size=2 face="Courier New" title="http://www.washcas.org/"><span
style='font-size:10.0pt;font-family:"Courier New"'>www.washcas.org</span></font></a><br>
<font size=2 face="Courier New"><span style='font-size:10.0pt;font-family:"Courier New"'>Email:
</span></font><a href="mailto:cleary@georgetown.edu"
title="mailto:cleary@georgetown.edu"><font size=2 face="Courier New"
title="mailto:cleary@georgetown.edu"><span style='font-size:10.0pt;font-family:
"Courier New"'>cleary@georgetown.edu</span></font></a><br>
<font size=2 face="Courier New"><span style='font-size:10.0pt;font-family:"Courier New"'>-------------------------------------------------------------------</span></font><o:p></o:p></p>
<p class=MsoNormal><font size=3 face="Times New Roman"><span style='font-size:
12.0pt'><o:p> </o:p></span></font></p>
</blockquote>
<!--[object_id=#accuray.com#]-->
<p class=MsoNormal style='margin-left:.5in'><em><b><i><font size=2 color=black
face=Arial><span style='font-size:10.0pt;font-family:Arial;color:black;
font-weight:bold'>WARNING CONFIDENTIAL INFORMATION:<o:p></o:p></span></font></i></b></em></p>
<p class=MsoNormal style='margin-left:.5in'><em><i><font size=1 color=navy
face=Arial><span style='font-size:9.0pt;font-family:Arial;color:navy'>The
information contained in the e-mail may contain confidential and privileged
information and is intended solely for the use of the intended
recipient(s). Access for any review, re-transmission, dissemination or
other use of, or taking of any action in regard and reliance upon this e-mail
by persons or entities other than the intended recipient(s) is unauthorized and
prohibited. If you are not the intended recipient, please contact the
sender by reply e-mail and destroy all copies of the original message and any
attachments.</span></font></i></em><font color=navy><span style='color:navy'><o:p></o:p></span></font></p>
</blockquote>
</blockquote>
</div>
</body>
</html>