<html><head><meta http-equiv="Content-Type" content="text/html charset=us-ascii"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;">Hans,<div><br></div><div><br></div><div><br></div><div>I have see a single per-pixel dynamic memory/malloc cause a 10X performance penalty. Also I have found apple Instruments easy for diagnosing this bottle neck. This is one possibility among many.</div><div><br></div><div>Good luck tracking down the issue.</div><div><br></div><div>Brad</div><div><br><div><div>On Apr 16, 2014, at 9:10 PM, Johnson, Hans J <<a href="mailto:hans-johnson@uiowa.edu">hans-johnson@uiowa.edu</a>> wrote:</div><br class="Apple-interchange-newline"><blockquote type="cite">
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<div>FYI</div>
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<div style="font-family: Consolas; font-size: 12px;">Ali Ghayoor did the following experiments on "BRAINSFitTest_BSplineScaleRotationRescaleHeadMasks" test.</div>
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<div style="font-family: Consolas; font-size: 12px;">1) In one of my old build directories, I ran the "BRAINSFitTest_BSplineScaleRotationRescaleHeadMasks" test in BRIANSFitv3 (that uses ITKv3 registration framework). The test was passed successfully in both
release and debug types, and it took:</div>
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<div style="font-family: Consolas; font-size: 12px;">22 second in release</div>
<div style="font-family: Consolas; font-size: 12px;">88 second in debug</div>
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<div style="font-family: Consolas; font-size: 12px;">2) I built NAMICExternalProject on my system in release type and ran the above BSpline test in BRAINSTools. The test was passed successfully again, but the run time in ITKv4 is tremendously longer than
the time that test takes in ITKv3. The test took:</div>
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<div style="font-family: Consolas; font-size: 12px;">18 minutes using 4 cores</div>
<div style="font-family: Consolas; font-size: 12px;">22 minutes using 1 core (In this case the environmental variable "NSLOTS" is set to 1).</div>
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<div style="font-family: Consolas; font-size: 12px;">Basically trying to replicate in ITKv4 the same registration processes of ITKv3.</div>
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<div style="font-family: Consolas; font-size: 12px;">Hans</div>
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